Vitamin B3 Analogue May Boost Cancer Immunotherapy

Stressors encountered in the tumor microenvironment—chronic stimulation by cancer antigens, PD-1 signaling, and the metabolic stress of nutrient and oxygen deprivation—can drive tumor-infiltrating T cells to exhaustion. Preventing or reversing this exhaustion may be possible with a nutritional approach that counters an underlying mechanism, the accumulation of dysfunctional mitochondria.

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Published on Mon, 05 Oct 2020 22:15:25 +0000 and sponsored by power automate count array