New CRISPR Baby Risk: Chromosome Loss

Applying CRISPR-Cas9 to repair a blindness-causing gene in a human embryo often eliminates an entire chromosome or a large section of it, report Columbia University scientists. These losses occur depending on how an induced double-strand break is repaired, suggesting that alternative approaches, such as base or prime editing, may be preferred in some applications.

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Published on Tue, 03 Nov 2020 22:15:44 +0000 and made possible by salesforce array starts with string