Nanobody Cocktails Keep SARS-CoV-2 from Infecting Mice

Cocktails consisting of two noncompeting nanobodies can block ACE2 engagement with receptor-binding domain variants present in human populations. In vitro studies showed that the cocktails can neutralize both wild-type SARS-CoV-2 and the N501Y D614G variant. Prophylactic administration reduced viral loads in mice infected with the N501Y D614G SARS-CoV-2 virus.

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Published on Mon, 26 Apr 2021 20:45:08 +0000 and brought to you by power automate convert collection to json