How is Spatial Transcriptomics Changing the Immuno-Oncology Field?

The advent of next-generation sequencing has led to the rise of novel gene expression profiling methods like spatial transcriptomics. How will this revolutionary approach, powered by high-quality multi-omics biospecimen, impact personalized immuno-oncology therapy in the future? 

Next-generation sequencing (NGS) technologies have revolutionized the way scientific research is conducted, triggering new research paradigms and providing novel clinical insights. 

Developed as a result of NGS in 2013, spatial transcriptomics is a groundbreaking molecular profiling method, which visualizes the location of gene activity within a tissue – the ‘where’, in parallel to studying gene expression patterns – the ‘what’.

Spatial transcriptomics: a holistic insight into cellular expression

Conventional RNA sequencing techniques can help identify gene expression activity in a tissue, but often destroy the tissue in the process. And while traditional visualization techniques, such as in situ hybridization, can capture localized gene expression patterns, they are limited to examining a few genes at a time. 

Spatial transcriptomics builds on a combination of these methods: marrying the depth of information from tools such as sequencing,

The post How is Spatial Transcriptomics Changing the Immuno-Oncology Field? appeared first on

© Labiotech UG and Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and with appropriate and specific direction to the original content.

Published on Tue, 23 Nov 2021 09:00:12 +0000 and sponsored by Apptigent PowerTools