Finding gene neighbors leads to new protein functions

Access to sequenced genomes was a watershed moment in life science research. Genome sequences spell out an organism’s DNA, the genetic code for how the organism develops, reproduces, and functions. As new technologies have developed, the availability of these gene sequences has grown exponentially. Unfortunately, scientists’ ability to decipher the functions encoded in these sequences has not kept pace. This is particularly true for eukaryotes—cells and organisms with clearly defined nuclei. As a result, researchers do not understand the function of millions of proteins, which do the work encoded in DNA. This challenge requires researchers to develop computational tools for predicting the function of gene sequences. In this study, researchers working with green algae discovered that physically clustered genes in eukaryotic genomes can be maintained over hundreds of millions of years. This phenomenon can help predict function.

Published on Tue, 06 Apr 2021 08:03:11 EDT and brought to you by power automate convert currency